QB Tom Brady (New England) vs Tampa Bay
- He's hurt and they are facing a very tough defense.

QB Ben Roethlisberger (Pittsburgh) vs Minnesota
- A bad thumb could force them to run the ball more than usual.

QB Drew Bledsoe (Dallas) vs Washington
- Bledsoe is facing a fiesty defense that likes to blitz.

QB Chris Simms (Tampa Bay) vs New England
- Simms has been good lately, but he will face his toughest test against the Pats.

QB Steve McNair (Tennessee) vs Seattle
- He's banged up and facing a defense that has been good all season.

RB Edgerrin James (Indianapolis) vs San Diego
- Of all the Indy players, James is the most likely to see a reduced work load.

RB Willis McGahee (Buffalo) vs Denver
- Still not living up to his own prophecies, McGahee won't do much against Denver either.

RB Domanick Davis (Houston) vs Arizona
- A knee injury might keep him on the bench this week. If he does play, he could come up big or suffer with a bad wheel.

WR Joe Horn (New Orleans) vs Carolina
- Without Aaron Brooks, don't think of playing Horn.