Round 1
- Detroit Lions – DT Ed Oliver (Houston)
- Buffalo Bills – DE Nick Bosa (Ohio State)
- Arizona Cardinals – OT Jonah Williams (Alabama)
- New York Giants – QB Justin Herbert (Oregon)
- Seattle Seahawks – CB Greedy Williams (LSU)
- Houston Texans – OT Greg Little (Ole Miss)
- Oakland Raiders – DE Clelin Ferrell (Ohio State)
- Pittsburgh Steelers – DE/OLB Montez Sweat (Mississippi State)
- New York Jets – DE/OLB Blair Burns (Florida State)
- Dallas Cowboys – S Deionte Thompson (Alabama)
- Indianapolis Colts – DE/DT Rashan Gary (Michigan)
- Oakland Raiders (from Bears) – LB Devin White (LSU)
- Tennessee Titans – OG/C Michael Deiter (Wisconsin)
- San Francisco 49ers – S Taylor Rapp (Washington)
- Carolina Panthers – DT Dexter Lawrence (Clemson)
- New England Patriots – DE/DT Raekwon Davis (Alabama)
- Los Angeles Chargers – LB Josh Allen (Kentucky)
- Atlanta Falcons – DT Dre’Mont Jones (Ohio State)
- Baltimore Ravens – WR A.J. Brown (Ole Miss)
- Green Bay Packers (from Saints) – OG Dalton Risner (Kansas State)
- Washington Redskins – CB Deandre Baker (Georgia)
- Philadelphia Eagles – LB Cameron Smith (USC)
- Cleveland Browns – CB Amani Oruwariye (Penn State)
- Green Bay Packers – QB Ryan Finley (NC State)
- Miami Dolphins – WR Marquise Brown (Oklahoma)
- Denver Broncos – DE Zach Allen (Boston College)
- Tampa Bay Buccaneers – DE Joe Jackson (Miami, FL)
- Cincinnati Bengals – QB Drew Lock (Missouri)
- Kansas City Chiefs – CB/S Julian Love (Notre Dame)
- Minnesota Vikings – OG Michael Jordan (Ohio State)
- Jacksonville Jaguars – OT David Edwards (Wisconsin)
- Los Angeles Rams – DT Jeffery Simmons (Mississippi State)